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Neuromelanin biosynthesis is driven by excess cytosolic catecholamines not accumulated by synaptic vesicles

doi: 10.3389/fphar.2021.570520 508 CeccarelliGStatzuMSantinelliLPinacchioCBitossiCCavallariENet al

Up to know, the majority of established and newly synthesized GST inhibitors have been primarily tested for their cytotoxic effect in cancer cell lines and mouse xenograft models, showing promising activities

IL-2-neutralizing antibodies, 25 g ml 1 S4B6 (BioXCell) and 25 g ml 1 JES6.1 (BioXCell) were directly added after activation in non-arrested conditions or after removal of the cell cycle inhibitor in released conditions